Бәсекелесті ингибирленген кезде ингибитор фермент-субстрат кешенімен, бірақ ерікті ферментпен байланысып, реакция жүргізуге кедергі береді 234. Бұл реакция жылдамдықтарын — Vmax және Михаэлис константасын — өзгертіп, ферменттің субстратқа жақындығын (Km) төмендетеді 35.
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